Eran Mukamel

Assistant Professor

Computational analysis of large-scale neural data, electrophysiology of sleep and general anesthesia, computational epigenomics in brain cells.

Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus.
Tie-Yuan Zhang†*, Christopher L. Keown†, Xianglan Wen, Junhao Li, Dulcie A. Vousden, Christoph Anacker, Urvashi Bhattacharyya, Richard Ryan, Josie Diorio, Nicholas O'Toole, Jason P. Lerch, Eran A. Mukamel*, Michael J. Meaney. (2018) 
Nature Communications 9:298, doi:10.1038/s41467-017-02748-x
†Equal contributions
*Corresponding authors
Data browser: http://brainome.ucsd.edu/mouse_dentategyrus

 

Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex.
Chongyuan Luo†, Christopher L. Keown†, Laurie Kurihara, Jingtian Zhou, Yupeng He, Junhao Li, Rosa Castanon, Jacinta Lucero, Joseph R. Nery, Justin P. Sandoval, Brian Bui, Terrence J. Sejnowski, Timothy T. Harkins, Eran A. Mukamel*, M. Margarita Behrens*, Joseph R. Ecker* Science 357:600-604
†Equal contributions
*Corresponding authors
[Pubmed] [Article]
Project website, including data and browsers: http://brainome.org

 

Allele-specific non-CG DNA methylation marks domains of active chromatin in female mouse brain.
Keown, C.L., Berletch, J.B., Castanon, R., Nery, J.R., Disteche, C.M., Ecker, J.R., Mukamel, E.A. (2017) PNAS. 2017; E2882-E2890, doi: 10.1073/pnas.1611905114. [Pubmed] [Article]